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B7������CD28/CTLA4��Ϻ�����Ĺ��̼��ź���Tϸ���������������ı�Ҫ����.ϵͳ�Ժ���Ǵ��������ڿ�ԭ�ݳ�ϸ�����B7�����쳣,����ϵͳ�Ժ���Ǵ����������й�.���B7/CD28�ź�ͨ·��ϵͳ�Ժ���Ǵ�����ģ����ȡ�������õ���Ч,������ܾ���DZ�ڵ��ٴ�Ӧ�ü�ֵ.
[2] Folzenlogen D, Hofer MF, Leung DY, et al. Analysis of CD80 and CD86expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. Clin Immunol Immunopathol, 1997,83(3): 199-204.
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