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[2] Pittelkow MR,Cook PW,Shipley GD,et al.Autonomous growth of human keratinocytes requires epidermal growth factor receptor occupancy.Cell Growth Differ,1993,4(6):513-521.
[3] Peus D,Hamacher L,Pittelkow MR,et al.EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation.J Invest Dermatol,1997,109(6):751-756.
[4] Kobayashi T,Hashimoto K,Okumura HJ,et al.Endogenous EGF-family growth factors are necessary for the progression from the G1 to S phase in human keratinocytes.J Invest Dermatol,1999,111:616-620.
[5] Cook PW,Piekorn M,Clegg CH,et al.Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype.J Clin Invest,1997,100(9):2286-2294.
[6] Rodeck U,Jost M,Kari C,et al.EGF-R dependent regulation of keratinocyte survival.J Cell Sci,1997,110(Pt 2):113-121.
[7] Wakita H,Takigawa M.Activation of epidermal growth factor receptor promotes late terminal differentiation of cell-matrix interaction-disrupted keratinocytes.J Biol Chem,1999,274(52):37285-37291.
[8] Wrone-Smith T,Mita RS,Thompson CB,et al.Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin.Am J Pathol,1997,151(5):1321-1329.
[9] Jost M,Class R,Kari C,et al.A central role of Bcl-X(L) in the regulation of keratinocyte survival by autocrine EGFR ligands.J Invest Dermatol,1999,112(4):443-449.
[10] Varani J,Kang S,Stoll S,et al.Human psoriatic skin in organ culture:comparison with normal skin exposed to exogenous growth factors and effectors of an antibody to the EGF receptor.Pathobiology,1998,66(6):253-259.
[11] Powell TJ,Ben-Bassat H,Klein BY,et al.Growth inhibition of psoriatic keratinocytes by quinazoline tyrosine kinase inhibitors.Br J Dermatol,1999,141(5):802-810.
[12] Krane JF,Gottlieb AB,Carter DM,et al.The insulin-like growth factor �� receptor is overexpressed in psoriatic epidermis,but is differentially regulated from the epidermal growth factor receptor.J Exp Med,1992,175(4):1081-1090.
[13] Nanney LB,Yates RA,King LE,et al.Modulation of epidermal growth factor receptors in psoriatic lesions during treatment with topical EGF.J Invest Dermatol,1992,98(3):296-301.
[14] Valyi-Nagy I,Jensen PJ,Albelda SM,et al.Cytokine-induced expression of transforming growth factor-��and the epidermal growth factor receptor in neonatal skin explants.J Invest Dermatol,1992,99(3):350-356.
[15] Gottlieb AB,Khandke L,Krane JF,et al.Anthralin decreases keratinocyte TGF-��expression and EGF-receptor binding in vitro.J Invest Dermatol,1992,98(5):680-685.
[16] Boisseau-Garsaud AM,Donatien P,Margerin C,et al.EGF receptor expression and growth of psoriatic and normal human keratinocytes are modulated by 1.25(OH)2-vitamin D3 ex vivo.Arch Dermatol Res,1996,288(8):453-457.
[17] Krane JF,Murphy DP,Martin Carter D,et al.Synergistic effects of epidermal growth factor(EGF) and insulin-like growth factor ��/somatomedin C(IGF-��) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor.JInvest Dermatol,1991,96(4):419-424.
[18] Vardy DA,Kari C,Lazarus GS,et al.Induction of autocrine epidermal growth factor receptor ligands in human keratinocytes by insulin/insulin-like growth factor.J Cell Physiol,1995,163(2):257-265.
[19] Stoll S,Garner W,Elder J,et al.Heparin-binding ligands mediate autocrine epidermal growth factor receptor activation in skin organ culture.J Clin Invest,1997,100(5):1271-1281.
[20] Marques MM,Martinez N,Rodriguez-Garcia I,et al.EGFRfamily-mediated signal transduction in the human keratinocyte cell line HaCaT.Exp Cell Res,1999,252(2):432-438.
[21] Choi JH,O'Connor TP,Kang S,et al.Activation of ribosomal protein S6 kinase in psoriatic lesions and cultured human keratinocytes by epidermal growth factor receptor ligands.J Invest Dermatol,1997,108(1):98-102.