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| PubMed | |
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Article by Guan,H.H |
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Article by Li,H.X |
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Article by Lin,l |
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Hair follicle stem cells in disorders characterized by alopecia
Alopecia, as a common disease, is generally classified into two groups, cicatricial and noncicatricial alopecia, according to clinical presentations and regrowth capability of hairs, and each group includes various types of alopecia. The pathogenesis of alopecia remains poorly understood. Hair follicle stem cells are located in the bulge area, whose periodic proliferation and differentiation sustain the growth, shedding and regrowth of hairs. Recent research has indicated that the damage or deficiency of hair follicle stem cells may contribute to the pathogenesis of some types of alopecia, especially cicatricial alopecia.
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