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| PubMed | |
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Article by Chen,g |
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Article by Lin,t |
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Article by Qu,m |
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Article by Xu,X.L |
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Article by Xun,J.P |
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Article by Zeng,H.S |
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Four cases of nevoid hyperkeratosis of the nipple and areola
Objective To report 4 cases of nevoid hyperkeratosis of the nipple and areola. Methods Clinical and histopathological manifestations of 4 cases of nevoid hyperkeratosis of the nipple and areola were observed and retrospectively analyzed. Results Of the 4 patients, 1 was male and 3 were female. The average age and disease duration were 32 and 4.5 years respectively. All cases showed hyperkeratosis and verrucous hyperplasia of the nipple and/or areola. Histopathology showed epidermal hyperkeratosis, papillomatous hyperplasia and elongation of the epidermal rete ridges. Conclusions Nevoid hyperkeratosis of the nipple and areola, a subtype of the hyperkeratosis of the nipple and areola, is uncommon in clinic and occurs mainly in young women with characteristic clinical and histological features.