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| PubMed | |
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Article by Xue,Y.N |
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Article by Zeng,H.S |
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Article by Gu,L.X |
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Article by Chen,g |
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Article by Li,A.M |
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Article by Shao,X.B |
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Article by Xun,J.P |
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Ŀ�� �о�̽��3���Լ���������ԭ�����鷿��Paget���б����ص㼰���塣 ���� �����黯������ۼ������塢�Ƽ���������м���������30��ԭ�����鷿��Paget���еı� ��� 30��ԭ�����鷿��Paget����19���ۼ������������ԣ�������Ϊ63.3%������25�����Ի�����������Ϊ72%��5��Ů�Ի�����������Ϊ20%�����⣬���в����дƼ���������м�����������Ա� ���� ԭ�����鷿��Paget���м��������ԣ��ۼ��ؼ���������ܲ���ԭ�����鷿��Paget���ķ����ͷ�չ��
Expressions of three sex hormone receptors in primary extramammary Paget′s disease and their significance
Objective To investigate the expression profiles of three sex hormone receptors including androgen receptor ��AR��, estrogen receptor ��ER�� and progesterone receptor ��PR�� in primary extramammary Paget′s disease ��EMPD�� and their significance. Methods Immunohistochemical methods were used to examine the expressions of androgen receptor, estrogen receptor and progesterone receptor in formalin-fixed paraffin-embedded tissue samples from 30 patients with EMPD. Results Androgen receptor was identified in 19 ��63.3%�� of the 30 tissue specimens, 18 ��72%�� of the 25 specimens from male patients, and 1 out of the 5 specimens from female patients. Neither estrogen receptor nor progesterone receptor was detected in any of these specimens. Conclusions EMPD is hormone-dependent. Andr
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