���ݾ����人��ҽԺ

Ƥ����ɫ�������������ԭ����Ƥ�����������ټ�����,��������ڱ����ı������٣��������ز���Ƥ����ɫ����������䷢������ȷ�������֯�����֧�֣���Ҫʱ���е羵�۲죬��������Ƥ����ɫ������ֵ�������������𡣻����ѱ����IJ���,�͸ò������ٴ��ص㡢��֯������ϼ�������ϵȷ������̽�֡�

Poilkiloderma-like cutaneous amyloidosis is a rare variant of primary amyloidosis and has been seldom reported at home and abroad. Numerous factors are involved in the development of poilkiloderma-like cutaneous amyloidosis. Histopathology is essentially required for its diagnosis, and electron microscopy is sometimes needed. Differential diagnosis should include other diseases with poilkilodermatous skin lesions. In view of reported cases, the authors describe the etiology, clinical features, histopathology, diagnosis and differential diagnosis of poilkiloderma-like cutaneous amyloidosis.

[1] Ho MH��Chong LY��Poikiloderma-like cutaneous amyloidosis in an ethnic Chinese gir1��J Dermatol��1998 ��2 5 (11 ) ��730 -734 �� [2] Pardo Arranz L��Escalonilla Garcia-Patos P��Roman Curto C et al. Familial poikylodermic cutaneous amyloidosis.; Eur J Dermatol. 2008��18��3����289-291 [3] Eswaramoorthy V, Kaur I��Das A et al�� Macular Amyloidosis ��Etiological Factors ��J Dermatol��1999��26��305 -310 �� [4] Yoshida A, Takahashi K; Lichen amyloidosis induced on the upper back by long-term friction with a nylon towel. ��J Dermatol. 2009 , 36(1): 56-59 [5] Ogino A, Tanaka S��Poikiloderma-like cutaneous cutaneous amyloidosis��Dermatologica. 1977,155��301-309. [6] Wang,-W-J��Chang,-Y-T��et al��Clinical and histopathological characteristics of primary cutaneous amyloidosis in 794 Chinese patients ��Zhonghua-Yi-Xue-Za-Zhi-(Taipei). 2001,64(2): 101-7 [7] Cheung ST, Maheshwari MB; A comparative study of two Congo red stains for the detection of primary cutaneous amyloidosis. J Am Acad Dermatol. 2006 , 55(2):363-364 [8] MacDonald DM, Black MM, Ramnarain N��Immunofluorescence studies in primary localized cutaneous amyloidosis��Br J Dermatol. 1977.96(6) ��635-641 [9] Rocken C, Shakespeare A; Pathology, diagnosis and pathogenesis of AA amyloidosis.��Virchows Arch. 2002,440(2): 111-122 [10] Chang YT, Tsai SF , Wang WJ; A study of apolipoproteins E and A-I in cutaneous amyloids. Br J Dermatol. 2001 , 145(3): 422-427 [11] Lee Y S, Fong P H. Sencondary localized amyloidosis in trichoepithelioma:a light microscopic and ultrastructural study. Am J Dermatol, 1990,12(5) ��469-478. [12] Lai KW, Lambert E, et al; Nodular amyloidosis: differentiation from colloid milium by electron microscopy. Am J Dermatopathol. 2009, 31(5): 472-474 [13] Larizza L, Roversi G, Volpi L. Rothmund-Thomson sydrome��Orphanet J Rare Dis. 2010, 5:2 [14] Yusuf SM, Mijinyawa MS; Dyschromatosis universalis hereditaria in a young Nigerian female. Int J Dermatol. 2009 , 48(7): 749-750 [15] Shono S��Toda K��Universal dyschromatosis associated with photosensitivity and neurosensory hearing defect ��Arch Dermotol,1990,126(12) ��1659-1600. [16] Yang JH, Wong CK. Dyschromatosis universalis with X-linked ocular albinism ��Clin Exp Dermatol,1991,16(6) ��436-440. [17] Pavithran K. Dyschromatosis universalis hereditaria with epilepsy ��Indian J Dermatol Venereol Leprol. 1991,57(2) ��102-103. [18] Vijaikumar M; Amyloidosis cutis dyschromica in two siblings; Clin Exp Dermatol.2001, 26(8):674-676 [19] Lai-Cheong JE, McGrath JA. Kindler syndrome��Dermatol Clin. 2010 , 28(1):119-124