1. ��ž���ҽԺƤ����
2. ������ž���ҽԺƤ����

����Խ��Խ��������ѡ��Ƥ���������޸��沿�ϻ�����ʹ��������Ƥ�����������������ࡣ��ĿǰΪֹ������ʳƷҩƷ�������׼�˽�ԭ��ţ��ԭ��͸�����ᡢ���������ᡢ�����׻�ʯ��ΪƤ���������ڻָ�����������沿���Ƽ�֬��ή������ЩƤ���������и��Բ�ͬ����Ӧ֤����ȱ���ά��ʱ�䣬����Щ�����Բ����������Ƥ���������ٴ�ҽʦӦ��������ߵľ���������Կ��ǣ�ѡ���ʺϵ������Դﵽ���������Ч����

Now, more and more people choose skin fillers to rejuvenate aging face, which contributes to the increase in variety of skin fillers. Up to now, United States Food and Drug Administration has approved human collagen, bovine collagen, hyaluronic acid, poly-L-lactic acid and calcium hydroxyapatite as skin fillers for age-related facial wrinkles and fat atrophy. These fillers have different indications, advantages, disadvantages and durability, but they are far from ideal. Doctors should consider the specific condition of patients before selecting the optimal fillers to product satisfactory cosmetic results.

null

�ο����ף� 1.Burgess CM. Principles of soft tissue augmentation for the aging face. Clin Interv Aging. 2006;1(4):349-55. 2.Buck DW 2nd, Alam M, Kim JY. Injectable fillers for facial rejuvenation: a review. J Plast Reconstr Aesthet Surg. 2009 Jan;62(1):11-8. Epub 2008 Oct 31. 3.Tiffani K. Hamilton MD.Skin augmentation and correction: the new generation of dermal fillers—A dermatologist's experience. Clinics in Dermatology. 2009 May-June;27(3):S13-S22 4.Johl SS, Burgett RA. Dermal filler agents: a practical review. Curr Opin Ophthalmol. 2006 Oct;17(5):471-9. 5. Sadick N, Sorhaindo L. The utility of soft tissue fillers in clinical dermatology: treatment of fine wrinkles and skin defects. Expert Rev Med Devices. 2007 Jul;4(4):559-65. 6.Lowe NJ, Maxwell CA, Patnaik R. Adverse reactions to dermal fillers: review. Dermatol Surg. 2005 Nov;31(11 Pt 2):1616-25. 7.Dadzie OE, Mahalingam M, Parada M, El Helou T, Philips T, Bhawan J. Adverse cutaneous reactions to soft tissue fillers--a review of the histological features. J Cutan Pathol. 2008 Jun;35(6):536-48. Epub 2008 Jan 14. 8. McCracken MS, Khan JA, Wulc AE, Holds JB, Fante RG, Migliori ME, Ebroon DA, Amato MM, Silkiss RZ, Patel BC. Hyaluronic acid gel (Restylane) filler for facial rhytids: lessons learned from American Society of Ophthalmic Plastic and Reconstructive Surgery member treatment of 286 patients. Ophthal Plast Reconstr Surg. 2006 May-Jun;22(3):188-91. 9.Eppley BL, Dadvand B. Injectable soft-tissue fillers: clinical overview. Plast Reconstr Surg. 2006 Sep 15;118(4):98e-106e. 10.Gold MH. Use of hyaluronic acid fillers for the treatment of the aging face. Clin Interv Aging. 2007;2(3):369-76. 11.Jacinto SS. Ten-year experience using injectable silicone oil for soft tissue augmentation in the Philippines. Dermatol Surg. 2005 Nov;31(11 Pt 2):1550-4; discussion 1554. 12.Salles AG, Lotierzo PH, Gimenez R, Camargo CP, Ferreira MC. Evaluation of the poly-L-lactic acid implant for treatment of the nasolabial fold: 3-year follow-up evaluation. Aesthetic Plast Surg. 2008 Sep;32(5):753-6. Epub 2008 Jun 13.