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Ŀ�� ����CO2 ������5-����ͪ����⶯���Ʒ���ALA-PDT���������Ƽ���ʪ�����Ч�������ԡ����� 124������ʪ�໼�������Ϊ���飬ÿ��62�������������CO2 ������ALA-PDT�������ƣ������鵥��CO2 �������ơ� ��� �����黼��Ȭ����Ϊ90.6% ��58/62����������Ϊ9.4%��4/62����������Ȭ����Ϊ76.7%��46/62����������Ϊ23.3%��16/62���� ������Ȭ���ʼ��������ϲ�����ͳ��ѧ���塣����CO2 ��������5-����ͪ����⶯���Ʒ����Ƽ���ʪ������Ч�������ʷ�����������ڵ���CO2 �������ơ�

Objective To evaluate the effect of CO2 laser in combination with 5-aminolevulinic acid-photodynamic therapy ��ALA-PDT�� on clearance and recurrence of condyloma acuminatum ��CA��. Methods A total of 124 patients with CA were randomly and equally divided into two groups to be treated with CO2 laser plus ALA-PDT ��test group�� or CO2 laser only ��control group��. Results The cure rate and recurrence rate were 90.6% ��58/62�� and 9.4% ��4/62��, respectively in the test group, 76.7% ��46/62�� and 23.3% ��16/62��respectively in the control group. There was a statistical difference in the cure rate and recurrence rate between the two groups ��both P < 0.05��. Conclusion CO2 laser in combination with ALA-PDT is superior to CO2 laser alone in the treatment of CA.

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